| Date | Location | Result | |
| 03/04/18 | Cotterell Court, Hamilton, N.Y. | Colgate 62, Holy Cross 55 | Box score |
| 03/01/18 | Alumni Hall, Annapolis, Md. | Holy Cross 81, Navy 65 | Box score |
| 02/24/18 | Cotterell Court, Hamilton, N.Y. | Colgate 59, Holy Cross 53 | Box score |
| 02/21/18 | Hart Center, Worcester, Mass. | Holy Cross 70, American 64 | Box score |
| 02/17/18 | Hart Center, Worcester, Mass. | Bucknell 68, Holy Cross 67 (OT) | Box score |
| 02/14/18 | Christl Arena, West Point, N.Y. | Holy Cross 70, Army West Point 65 | Box score |
| 02/10/18 | Case Gymnasium, Boston, Mass. | Holy Cross 73, Boston University 62 | Box score |
| 02/07/18 | Hart Center, Worcester, Mass. | Navy 69, Holy Cross 34 | Box score |
| 02/03/18 | Reitz Arena, Baltimore, Md. | Holy Cross 73, Loyola (Md.) 57 | Box score |
| 01/29/18 | Hart Center, Worcester, Mass. | Lehigh 71, Holy Cross 67 | Box score |
| 01/27/18 | Hart Center, Worcester, Mass. | Holy Cross 85, Lafayette 74 | Box score |
| 01/22/18 | Bender Arena, Washington, D.C. | Holy Cross 60, American 57 | Box score |
| 01/20/18 | Sojka Pavilion, Lewisburg, Pa. | Bucknell 77, Holy Cross 56 | Box score |
| 01/17/18 | Hart Center, Worcester, Mass. | Holy Cross 70, Army West Point 66 | Box score |
| 01/14/18 | Hart Center, Worcester, Mass. | Boston University 54, Holy Cross 40 | Box score |
| 01/11/18 | Alumni Hall, Annapolis, Md. | Navy 61, Holy Cross 56 (OT) | Box score |
| 01/08/18 | Hart Center, Worcester, Mass. | Holy Cross 64, Loyola (Md.) 57 | Box score |
| 01/05/18 | Stabler Arena, Bethlehem, Pa. | Lehigh 83, Holy Cross 77 | Box score |
| 01/02/18 | Kirby Sports Center, Easton, Pa. | Lafayette 60, Holy Cross 48 | Box score |
| 12/29/17 | Hart Center, Worcester, Mass. | Colgate 79, Holy Cross 74 | Box score |
| 12/22/17 | Times Union Center, Albany, N.Y. | Siena 71, Holy Cross 65 | Box score |
| 12/19/17 | Hart Center, Worcester, Mass. | Iona 82, Holy Cross 68 | Box score |
| 12/09/17 | Hart Center, Worcester, Mass. | Holy Cross 62, New Hampshire 58 | Box score |
| 12/06/17 | Mullins Center, Amherst, Mass. | Massachusetts 64, Holy Cross 50 | Box score |
| 12/02/17 | SSE Arena, Belfast, Northern Ireland | La Salle 58, Holy Cross 54 | Box score |
| 12/01/17 | SSE Arena, Belfast, Northern Ireland | Manhattan 70, Holy Cross 54 | Box score |
| 11/25/17 | Hart Center, Worcester, Mass. | Albany 78, Holy Cross 62 | Box score |
| 11/22/17 | Rothman Center, Hackensack, N.J. | Fairleigh Dickinson 87, Holy Cross 76 | Box score |
| 11/19/17 | Ryan Center, Kingston, R.I. | Rhode Island 88, Holy Cross 66 | Box score |
| 11/16/17 | Hart Center, Worcester, Mass. | Holy Cross 73, Harvard 69 | Box score |
| 11/10/17 | Pitt Center, Fairfield, Conn. | Holy Cross 69, Sacred Heart 64 | Box score |